Log In|Sign Up
EN
A cDNA encoding the open reading frame with an A to T transversion at position 2958 that resulted in an amino acid substitution of phenylalanine for tyrosine at position 816 (Y816F) was inserted into the coding exon. A floxed neo cassette was also inserted downstream of the cDNA but was removed by subsequent germ-line, cre-mediated recombination. The amino acid substitution occures within the PLCgamma site. (J:130626)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
