A cassette containing a splice acceptor, frt-flanked neo cassette, floxed IRES-EGFP with a farnesyl modification, and human placental alkaline phosphatase was inserted into the ROSA locus. Expression of the membrane-bound EGFP occurs after flp-mediated excision and expression of the human placental alkaline phosphatase occurs after both flp- and cre-mediated recombination. (J:128980)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S4/SvJaeSor
Targeted
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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