A neo cassette flanked by frt sites with a 3' loxP site was inserted into intron 3 and an additional loxP site was inserted into intron 2 resulting in a floxed exon 3. The neo cassette was removed by germ-line, flp-mediated recombination. (J:130570)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count