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The second amino acid encoded by exon 3 was replaced with a stop translation codon and the remainder of exon 3 and exon 4 were replaced with an IRES Tau-LacZ and neo cassette. The absence of endogenous protein product was confirmed on E14.5 head and trunk extracts and E18.5 head extracts. Beta-galactosidase is not expressed from this allele. (J:130322)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
