A floxed neo cassette was inserted into intron 5-6 and additional loxP site was inserted into intron 1-2. This resulted in the floxing of exons 2 through 5. Transient Cre expression was used to removed the neo cassette. (J:131055)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count