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A floxed neo cassette was inserted 3' to exon 12 and an additional loxP site was inserted 5' to exon 12. Transient cre expression resulted in the excision of the neo cassette and exon 12. The absence of protein product was confirmed by western blot analysis on brain extracts and immunohistochemistry on the brain. (J:131058)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
