A floxed neo cassette was inserted into intron 1 and removed by cre-mediated recombination. A GFP cassette was also inserted in frame into exon 2 replacing the start codon. The expression of the fusion transcript and protein was confirmed by northern and western blot analysis at lower levels than normal. (J:131281, J:212391)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
Insertion, Intragenic deletion
--
1
3
47

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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