The coding region of Ednrb plus an frt-flanked puromycin resistance cassette was knocked into the neo cassette within exon 2 of Ednratm1Hku using RMCE. Expression of the knocked in allele was confirmed by RT-PCR of E9.5 mandible arches extracts. (J:131382)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129)F1
Targeted
Insertion
--
1
3
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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