The coding region of Ednrb plus an frt-flanked puromycin resistance cassette was knocked into the neo cassette within exon 2 of Ednratm1Hku using RMCE. Expression of the knocked in allele was confirmed by RT-PCR of E9.5 mandible arches extracts. (J:131382)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count