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A 1,787-bp human genomic DNA fragment of the CD11B gene containing 1704 bp of upstream DNA and the 83 bp encoding the 5' untranslated region drives expression of a cDNA comprising the 444-bp protein-coding sequence of mouse allograft inflammatory factor 1 (Aif1). Immunoblot analysis demonstrated transgene expression in the integrin alpha M/CD11B-positive cellular fraction and in lymphoid organs including spleen, lymph nodes and bone marrow. (J:126167)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
