A GFP cassette and a neomycin resistance cassette that is flanked by both loxP and FRT sites was inserted upstream of the ATG site of exon 2. The cassette replaces about 5kb of sequence, including exons 3 through 11. GFP expression was detected hematopoetic cell types with highest expression in B cells. (J:130017)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NTac
Targeted
Insertion, Intragenic deletion
--
1
--
8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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