RMCE using Ptf1atm1Mgn inserted a cre and mouse Esr1 (CreERTM) replacing exon 1 and 2 and a hygromycin resistance cassette downstream of exon 2. Flp-mediated recombination removed the FRT-flanked hygro cassette. (J:180310, J:194063)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
Insertion
--
1
4
45

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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