This transgene expresses a rat Atp2a2 cDNA under the control of a human cytomegalovirus immediate early enhancer linked to the chicken beta-actin minimal promoter. The transgene copy number is estimated to be 2, and the total amount of expressed RNA in heart ventricles is 2.6-fold higher than in control littermates. An additional transgenic line from founder CJ2 was also established. (J:107873)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
BALB/c x C57BL/6
--
Insertion
--
1
--
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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