This transgene expresses a rat Atp2a2 cDNA under the control of a human cytomegalovirus immediate early enhancer linked to the chicken beta-actin minimal promoter. The transgene copy number is estimated to be 2, and the total amount of expressed RNA in heart ventricles is 2.6-fold higher than in control littermates. An additional transgenic line from founder CJ2 was also established. (J:107873)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count