A loxP-flanked neomycin resistance cassette (Neo) is present in intron 1, upstream of the first coding exon (exon 2), and a third loxP site resides downstream of the fourth coding exon (exon 5). Partial Cre-mediated recombination in vivo was used to delete only the floxed Neo cassette and create the Tln1tm4.1Crit allele. (J:131145)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
Insertion
Recessive
1
--
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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