A floxed neo cassette was inserted into intron 5 and an additional loxP site was inserted into intron 6. The neo cassette and exon 6 were subsequently removed by cre-mediated recombination using a transiently expressing cre plasmid. (J:129552)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count