A floxed neo cassette was inserted into intron 18 and an additional loxP site was inserted into intron 17. The neo cassette was removed by cre-mediated recombination using a transiently expressing cre vector leaving a floxed exon 18. (J:129570)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count