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Using BAC RP23-446J14, the researchers replaced the Foxl1 open reading frame with an IRES-cre cassette and the Foxc2 gene with an frt-flanked kanamycin cassette to prevent any expression from it. The kanamycin was later removed by flp-mediated recombination. Cre is expressed in the mesenchymal cells of the stomach and intestines. (J:128623)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
