Murine Wnt4 coding sequence was inserted into the locus downstream of a floxed neomycin selection cassette. The neo cassette has five polyadenylation sequences preventing transcription of the Wnt4 gene. Upon cre expression, the neomycin cassette is removed and Wnt4 is expressed. (J:129327)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count