A floxed neo cassette was inserted downstream of exon 4 and an additional loxP site was inserted upstrem of exon 4. The floxed neo cassette was removed by cre-mediated recombination using a cre-expressing plasmid. (J:129038)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count