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Exon 5 was flanked by loxP sites with one loxP site placed immediately upstream and the other placed 600 bp downstream. A FRT-flanked neo selection cassette was placed between the exon and the downstream loxP site. Mice were crossed with FLP expressing knock-in mice to remove the neo cassette. Insertion of the loxP sites were presumed not to effect gene expression because homozygote mice were born at Mendelian frequencies. (J:128712)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
