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A human genomic clone containing the APOE*4 allele of the APOE gene, the APOC1 gene and the hepatocyte control region (HCR) located downstream of the APOC1 gene was used to create transgenic mice. Four transgenic lines were generated including lines 20, 43, 64, and 81. (J:109197)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
