A human genomic clone containing the APOE*3 allele of the APOE gene, the APOC1 gene and the hepatocyte control region (HCR) located downstream of the APOC1 gene was used to create transgenic mice. Five transgenic lines were generated including lines 393, 414, 428, 437, and 453. (J:109197)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6J x DBA/2J)F1
--
Insertion
--
2
--
16

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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