A targeting construct was used to flank exons 8 to 13 with loxP sites and insert an FRT-flanked NEO cassette into intron 13. The loxP flanked region is designed to remove amino acids 361 to 692, which encompasses a part of armadillo repeat 6 to a part of the C terminus. (J:232771)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Targeted
Insertion
--
1
22
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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