A targeting construct with the SA-attB-PGKneo 4xpA-attP-lacZ-pA cassette, in which the STOP fragment is flanked by attB and attP sites (phi31 recognition sites), was inserted into the Gt(ROSA)26Sor. Expression of the lacZ gene is blocked by a STOP fragment (flanked by attB and attP sites) placed between the lacZ sequence and the Gt(ROSA)26Sor promoter. PhiC31o-mediated recombination will excise the STOP and allow lacZ transcription. (J:128069)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S4/SvJaeSor
Targeted
Insertion
--
--
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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