A beta-geo gene trap vector inserted into intron 1. Western blot analysis confirmed the absence of protein expression in extracts from primary fibroblasts. In primary fibroblasts levels of phophatidylinositol 3,5-biphosphate and phophatidylinositol 5-phosphate are significantly reduced while levels of phophatidylinositol 3-phosphate are elevated. (J:127106)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
--
1
2
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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