2 independent constructs consisting of a 600 bp fragment of the 5' sequences driving the H2-Ead and a 600 bp fragment of 5' sequence driving the H2-Eb1b gene were coinjected into fertilized pronuclei. Four founders with germline transmission were identified and 3 (187-1, 187-7, and 190-5) were further studied. 187-7 (male) was chosen as representative, since it apparently characterized most thoroughly. (J:127706)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x SJL)F1
--
Insertion
--
--
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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