2 independent constructs consisting of a 600 bp fragment of the 5' sequences driving the H2-Ead and a 600 bp fragment of 5' sequence driving the H2-Eb1b gene were coinjected into fertilized pronuclei. Four founders with germline transmission were identified and 3 (187-1, 187-7, and 190-5) were further studied. 187-7 (male) was chosen as representative, since it apparently characterized most thoroughly. (J:127706)
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基础信息

模型ID
品系来源
等位基因类型
突变
遗传方式
基因表达
相关疾病
参考文献
(C57BL/6 x SJL)F1
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Insertion
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3

表型特征

标签摘要:
hm: 纯合子
ht: 杂合子
cn: 条件基因型
cx: 复合型:涉及多基因组
tg: 转基因
ot: 其他:半合子、不确定...
(F): 雌性
(M): 雄性
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N: 正常表型
(#): 上标括号内为相关疾病数量
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