A cre-inducible death cassette consisting of a loxP flanked stop codon upstream of a diphtheria toxin A coding sequence was introduced into the gene locus. Expression of cre recombinase will excise the stop codon leading to death of the cell. (J:127822)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count