The targeting construct contains the tamoxifen-inducible cre/Esr1 sequence under the control of the rat Nestin promoter. Line 4 shows postnatally inducible cre activity, in addition to inducible embryonic brain and spinal cord activity assayed by crossing the mice to mice carrying the ROSA26 reporter. (J:127227)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count