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A vector was designed to introduce two modified copies of exon 7 to the targeted gene. The first modified exon 7 carries a partial cDNA fragment of syntaxin with a C-terminal GFP and a stop codon. This mutation is followed by neomycin resistance cassette placed in intron 7 and flanked by flp sites. The first exon 7 insertion and the neomycin cassette are flanked by a pair of loxP sites. A second modified exon 7 bearing L165A and E166A mutations follows the neomycin insertion. (J:138035)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
