A targeting vector was used to introduce a Flp-flanked neomycin resistance cassette to intron 1 and a loxP-flanked green fluorescent protein (GFP) segment to exon 2 of the gene. The GFP segment was deleted from targeted animals through crosses with a Cre strain. (J:144771)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count