Myt1tm1Ggu mice were crossed with Tg(Sox2-cre)1Amc mice, excising the floxed exon (exon 9 for long transcript of gene, exon 3 for short transcript) in the germline. Inactivation of the gene was confirmed by ISH and RT-PCR of the pancreas in E18.5 embryos. (J:127471)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
Intragenic deletion
Recessive
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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