A FRT flanked pGK-Neo cassette and a loxP site was inserted upstream of exon 9 (or exon 3 when the short alternative transcript is being produced) and a third loxP site was inserted downstream of the exon. Mice were crossed with a Flpe deleter strain to remove the selection cassette, leaving the targeted exon flanked by loxP sites with one FRT site remaining upstream of the targeted exon but downstream of the first loxP site. (J:127471)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
Insertion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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