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The transgene construct contained the murine Tnf-alpha gene driven by the rat insulin 2 promoter (RIP). Founder mice carried the transgene with copy number ranging from 2-20 per genome. Line 17 was used for further study. Transcripts of the transgene were detected by Northern blot only in the pancreas of the mice. (J:91820)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
