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An 11.8-kb segment of the gene extending from 27 nucleotides in exon 2 through exon 3 was replaced with a beta-gal reporter gene and a loxP-flanked neomycin selection cassette. Quantitative RT-PCR on 9.5 embryos demonstrated no gene expression in homozygotes. Beta-gal expression was observed in the developing cardiovascular system. (J:125903)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
