The floxed neo cassette introduced into intron 5 was removed by cre-mediated recombination following a cross with Tg(ACTB-cre)13Miya mice. Western blot analysis on protein extracts from whole E9.5 embryos revealed wild-type levels of expression. (J:126471)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count