The genomic region between intron 4 and 5 was removed by cre-mediated recombination following the electroporation of embryonic stem cells with a transient cre-expression construct. The absence of protein product was confirmed by western blot analysis on protein extracted from whole E9.5 embryos. (J:126471)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count