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Exons 3 through 6 were flanked by loxP sites and a neo cassette flanked by frt sites was inserted 5' of exon 3. The neo cassette was removed by Flp-mediated recombination following a cross to Gt(ROSA)26Sortm1(FLP1)Dym mice. Southern blot analysis was performed to confirm the insertions. (J:126501)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
