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A transgenic construct containing sequence encoding Cre recombinase under the control of the mouse platelet derived growth factor receptor, beta polypeptide promoter and a SV40 polyadenylation site sequence was injected into fertilized CBA x C57BL/6J mouse eggs. Founder line 9 was established. Cre recombinase expression is detected mural cells (vascular smooth muscle cells and pericytes) of the skin, intestine, kidney, lung, and the CNS vascular plexus as well as other organs. (J:115909)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
