A floxed neo cassette replaced 2.8 kb of upstream sequence between -1.3 kb and -4.1 kb from the initiation site. The neo cassette was removed by cre-mediated recombination following a cross to Tg(EIIa-cre)C5379Lmgd mice. Insertion was confirmed by PCR genotyping on embryonic stem cells. (J:125994)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129P2/OlaHsd
Targeted
Intragenic deletion
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--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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