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EN
A cDNA encoding Cre recombinase with an N-terminal nuclear localization signal (nls) resides immediately 5' of the translation initiation site of the endogenous gene. This allele was derived from Emx1tm1(cre)Ito by FLP recombinase excision of a FRT-flanked pgk-neo cassette that lay immediately downstream of the nls-cre gene. The Emx1 promoter drives Cre recombinase expression in the embryonic through adult dorsal telencephelon; deletion of the selection cassette reportedly prevents ectopic expression in other brain regions. (J:64064, J:104881)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
