LoxP sites flank an Frt-flanked neo cassette and the part of exon 18 which codes for the transmembrane and signal-transducing domains. The neo cassette was then removed by Flp mediated recombination. (J:127019)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count