The transgene carries a floxed neo sequence, the baculovirus p35 coding sequence and a polyadenylation signal downstream of a chicken beta-actin promoter. Upon Cre-mediated excision of the loxP-neo-loxP sequence, the modified allele expresses p35 in tissues where Cre is expressed. (J:126593)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count