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Nucleotides 38 through 120 of the second exon were replaced with a stop codon followed by an IRES-EGFP and a floxed neo cassette. The neo cassette was subsequently removed by cre-mediated recombination following a cross to mice carrying the cre gene driven by a beta-actin promoter (allele not specified). The absence of protein product was confirmed by western blot analysis on proteins extracted from the lymph nodes and spleen. (J:126345)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
