Log In|Sign Up
EN
This transgene consists of a 1.1-kb fragment of the mouse Msx2 gene containing 0.3 kb of the 3.5-kb intron and a PCR-mutagenized version of the second exon bearing the Pro7His mutation under the control of the Timp1 promoter. This single base pair mutation is seen in individuals affected with Boston-type craniosynostosis. (J:26513)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
