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A mouse Hoxd11 trangene construct was modified by in-frame insertion of the Cre coding sequence, followed by the SV40 polyadenylation signal, at the start codon in exon 1 so that Cre recombinase is expressed under control of the Hoxd11 regulatory elements, but without any residues derived from Hoxd11. Homology arms were added to target integration to a site between Hoxd13 and Evx2, at the 5' extremity of the cluster. (J:82530)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
