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The construct uses the human prostate-specific antigen promoter (referred to as PSA; proper designation KLK3) to drive transcription of the cre recombinase cDNA. The transgene was injected into fertilized FVB oocytes. Prostate-specific expression was verified by crossing to Tg(ACTB-cat,-lacZ)34Pva transgenic mice. Founder line D4 showed high, prostate-specific cre activity. (J:99524)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
