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The first 3 exons were replaced by cDNA encoding lacZ and a pGK neo cassette, bringing the beta-galactosidase cDNA under the control of the endogenous promoter while ablating the endogenous gene. Northern and Western blot analysis on skeletal muscle and heart confirmed absence of Ankrd2 RNA and protein, respectively. (J:125819, J:215212)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
