Log In|Sign Up
EN
A 1.46 kb genomic region containing the E8iii enhancer element for the Cd8a gene was fused to 450bp of the Cd8a promoter and placed upstream of Cd4 cDNA. This transgene drives expression of CD4 in double positive T cells in the thymus. Expression in thymocytes was confirmed by crossing with mice that lack endogenous expression of CD4 and immunostaining for CD4. (J:100541)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
