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A "degradation resistant" human cyclin E cDNA was placed under the control of the human surfactant protein C promoter which causes expression in alveolar type II and bronchioalveolar cells. The protein expressed by this transgenes has a threonine for alanine substitution at amino acid residues 62 and 380. Transgenic protein was detected immunologically. Expression of this transgenic line occurs at a low level. (J:122698)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
