The 489 bp conserved enhancer between Il13 and Il4 was replaced with a loxP site flanked neomycin resistance gene cassette that was subsequently removed following a cross with Tg(MMTV-cre)1Mam mice. The absence of the enhancer was confirmed by Southern blot analysis. (J:125684)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129X1/SvJ
Targeted
Intergenic deletion
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--
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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