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The transgene consists of a 9-kb mouse genomic DNA fragment encompassing the coding region of the zinc finger protein of the cerebellum (Zic1) gene and 2.9 kb of 5' flanking DNA containing the proximal promoter and dorsal spinal cord enhancer, with a termination linker inserted 475 bp downstream of the initiation codon to terminate translation prematurely within the N -terminal region of the protein and with an IRES-lacZ cassette inserted into the gene's 3'-untranslated region. (J:76132)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
